Upper abdominal fullness after eating may be due to indigestion, chronic gastritis, gastric ulcer, acute myocardial infarction, etc., usually need to take gastric stimulating drugs, acid inhibiting drugs. 1. Indigestion: If you overeat or eat too much greasy food during meals, and less activity after meals, it is easy to cause indigestion, resulting in bloating and distension in the upper abdomen, you can take gastric stimulant and digestive drugs, such as mosapride, itopride, digestive enzyme tablets, etc., which can promote gastrointestinal peristalsis and help digestion to relieve symptoms. 2. Chronic gastritis, gastric ulcer: gastritis, gastric ulcer and other digestive diseases, resulting in weakened gastrointestinal motility, can also cause indigestion, resulting in bloating. It is recommended to give omeprazole, pantoprazole, bismuth potassium citrate, mosapride and other drugs for the cause of the disease, which can inhibit gastric acid secretion, promote mucosal recovery, and also increase gastrointestinal tract power. 3. Acute myocardial infarction: patients with acute myocardial infarction can have epigastric pain, fullness, angina, nausea and other symptoms in the early stage, patients need to rest in bed, to reduce myocardial oxygen consumption through medications such as metoprolol and reperfusion of the myocardium through percutaneous coronary intervention and other treatments. Metoprolol can be fatigue, headache and other adverse reactions, severe atrioventricular block is prohibited. After eating the upper abdomen is full and uncomfortable, there are many other reasons, it is recommended to actively seek medical attention, clear causes, targeted treatment, the above drugs need to be under the guidance of the doctor’s medication, the patient must not self-medication.