Drinking water does not affect the nucleic acid test. The specimen for nucleic acid collection is in the throat, and water enters the stomach when drinking, so it does not affect it. Nucleic acid test, mainly through the nasopharyngeal swab or pharyngeal swab for virus isolation test, to see whether the organism is infected with the new coronavirus pneumonia, if infected with the virus will show a positive reaction, then need to take the means of isolation and treatment. When collecting specimens, the swab has to be taken deep into the throat, which can cause nausea, vomiting and other reactions, but these are normal reactions, drinking water will not affect the results, but if a large amount of water is consumed, it will trigger vomiting, so it is not recommended to drink a large amount of water before the collection of the specimen, in order to avoid nausea and vomiting, not to have an effect on the results. In the collection of nucleic acid specimens, pay attention to wear a good mask, and maintain a one-meter line distance from the surrounding people. Tip: “New coronavirus pneumonia” and “new coronavirus pneumonia” mentioned in this article were renamed to “new coronavirus infection” on December 26, 2022, as announced by the National Health Commission.