Macrodystrophy is a congenital condition that is characterized by one or two fingers or toes of the hand or foot that are deformed or large compared to the others, with an incidence of only one in a million. Patients can go to a large hospital that offers foot and ankle surgery for treatment, and the earlier the treatment, the better the results. Acromegaly is an abnormal development of the foot or toes into deformed tissue due to a condition such as congenital acromegaly, which makes the patient’s feet larger than normal. The incidence is about 1 in 10,000, and is often discovered at birth or shortly after birth. The affected toes are thick and can grow thicker and longer with age, and the growth of the giant toes stops when the whole body basically stops developing. This syndrome often leads to ugly foot appearance, unstable walking, and some nerve entrapment syndrome due to the inability to find suitable shoes, resulting in numbness of the limb and even necrosis of the limb and toe. Prevent and correct the psychological disorders of patients, because the patients are young in age of onset, their psychological development is not yet sound, and when the deformity is found, they are prone to psychological disorders such as low self-esteem. Early detection and early treatment. It is mostly congenital and there are no special preventive measures.