Most HPV59 positives alone can heal themselves, however, some cannot. 1. Normal cervical TCT: HPV (human papillomavirus) 59 is a high-risk type of HPV, and its persistent infection is closely related to the development of cervical cancer. If HPV59 alone is positive, if the cervical cytology is normal and the woman’s immunity is normal, most women can be cured on their own, and even some women can turn negative without treatment. 2. Abnormal cervical TCT examination: at this time, the possibility of HPV59 positive self-cure is relatively small, you need to actively accept the treatment, according to the cytopathological typing to take personalized treatment. Simple HPV59 infection, if the TCT suggests that the cervix is low-grade intraepithelial neoplasia, only the local application of interferon therapy; if there is a high degree of intraepithelial neoplasia of the cervix, you need to take measures such as cervical conization. If the patient has HPV59 positivity, the doctor needs to decide how to further intervene in the treatment in conjunction with the cervical TCT results.