A lump in the vaginal opening with hardness is considered to be related to vestibular gland cysts, submucosal leiomyoma, condyloma acuminatum, vulvar tumors and so on. 1. Vestibular cysts: inflammation can lead to obstruction of the ducts of the vestibular glands, resulting in glandular fluid can not be discharged normally and the formation of local retention cysts, so the patient is more on the side of the vulva can be touched with a hard mass. 2. Submucous membrane fibroid: if the patient has a submucous membrane fibroid with clitoris, it may be detached from the uterine cavity, and some patients may touch a foreign object in the vagina or see a hard mass in the vaginal opening. 3. Condyloma acuminatum: If the vulva is infected with human papilloma virus, the local manifestation may be papules, cauliflower pattern or papillomavirus. 4. Vulvar tumors: if the patient has vulvar tumors, such as vulvar papilloma, fibroma, squamous cell carcinoma, etc., in addition to the symptoms of a hard lump on the vaginal opening, it can be accompanied by vulvar itching, ulcers, bleeding and so on. Patients who find a lump at the vaginal opening should go to the gynecology department of regular hospitals, complete relevant examinations, and under the guidance of doctors, actively treat the disease after clarifying the cause of the disease.