Tadalafil can generally be taken with dapoxetine, but one needs to be wary of decreased standing endurance, and use the medication as prescribed.
Tadalafil can be used to treat erectile dysfunction and should be contraindicated in those who are taking guanylate cyclase stimulators and nitrates, those whose loss of vision on one side is due to a non-arteritic ischemic lesion of the anterior part of the optic nerve, those who have cardiac disorders and are at risk of underlying disorders, and those who are allergic to the product. Adverse reactions such as nasal congestion, flushing, limb pain, back pain, dyspepsia, and myalgia are common.
Dapoxetine is used to treat poor ejaculatory control as well as premature ejaculation. It should be contraindicated in people who are allergic to the product, those with significant cardiac pathology, and those who experience moderate to severe liver injury. Common adverse reactions to the drug include headache, dizziness, nausea, diarrhea, insomnia, and fatigue.
There is generally no significant drug interaction between tadalafil and dapoxetine in combination, but a decrease in standing endurance may occur during co-administration, so it should be used with caution. Specific drugs should be used under the guidance of a specialist.