Drinking alcohol is inevitable in our daily life, but some people become addicted to it accidentally. When the addiction lasts for a long time, it will affect our daily life and work. When we become addicted to drinking and become “alcoholic” and still drink for a long time, we will get a disease called alcohol dependence. So how should alcohol dependence be treated? The first time I saw him, he started to drink more than 10 years ago, but the amount of alcohol he drank was small and intermittent, not affecting his work and life. Once drinking alcohol to drink pain, each drink lasted 2-3 days, sleep after drunkenness, when sober, sometimes they know that drunkenness will be out of the situation, and then gradually drinking alcohol addiction, a strong desire for alcohol, drinking alcohol seriously affect work and life. The use of various hair methods to quit drinking are not effective. Jin insisted on not drinking for more than 20 days and came to the neurosurgery department of the hospital for consultation, and was admitted to the hospital as “alcohol dependence”. After the disease, Jin’s mental status examination, clear consciousness, anxiety state is obvious, no perceptual syndrome, poor thinking logic. His memory was poor and he had poor sleep. The preliminary diagnosis was alcohol dependence. Jin was admitted to the hospital to actively improve the relevant examination and preoperative preparation, and there was no absolute contraindication to surgery in all preoperative examinations. Jin and his family voluntarily accepted the surgery to stop drinking and underwent stereotactic intracerebral multi-point radiofrequency disruption treatment under general anesthesia, and the procedure went smoothly. The patient recovered well after surgery. This shows that when we repeatedly stop drinking on our own with no effect, surgery is not a bad way to stop drinking. Regarding surgical withdrawal from alcohol addiction, the principle of surgical withdrawal from alcohol is the same as the principle of surgical detoxification, which uses a kind of localized targeted disruption based on modern physiological techniques and cellular localization, with remote sensing microdetermination of location and computer control, by analyzing the electrical signals in brain cells, and supplemented by advanced image diagnostic techniques such as MRI and spiral CT, so as to determine the best surgical procedure that causes addiction “target”, and then eliminate the addictive cells in the patient’s brain with radiofrequency heating to achieve the purpose of treatment.