Whether or not a urine albumin creatinine ratio of 60mg/g is serious depends mainly on its etiology and cannot be generalized. Physiological causes of urinary protein is usually not serious; pathologic causes of urinary protein without timely standardized intervention and treatment may appear disease progression, serious cases can be life-threatening, this time is more serious. The ratio of urine microalbumin to creatinine is less than 30mg/g in normal people, and when the patient’s test result is 60mg/g, it is mildly elevated. It is mainly seen in physiologic and pathologic two kinds. Physiological proteinuria is common in strenuous exercise, fever, etc., the patient’s kidneys have no organic lesions, after resting, urine protein can usually turn negative, usually does not appear to be a more serious situation. Pathological proteinuria is usually caused by organic lesions of the kidneys, and its common causes include glomerulonephritis, urinary tract infections, and urinary stones. If the primary disease is not timely and standardized treatment, it may cause the progression of the primary disease, which in turn aggravates proteinuria, the gradual decline in renal function, and in severe cases, may even lead to uremia, which is more serious at this time. If the patient found that the urine albumin creatinine ratio is high, it is recommended to go to the regular hospital in time, improve the examination to clarify the cause of the disease, and under the guidance of the doctor to target treatment or treatment.