Type II respiratory failure is characterized by partial pressure of oxygen <60 mmHg and partial pressure of carbon dioxide >50 mmHg. clinically, the most common causes of type II respiratory failure are chronic obstructive pulmonary disease and chronic pulmonary heart disease. patients diagnosed with type II respiratory failure can be treated with non-invasive ventilator therapy, and if non-invasive ventilator therapy is ineffective, invasive ventilator therapy can be adopted and oxygen can be administered at the same time. In addition to the above treatment methods, patients with acute exacerbation of chronic obstructive pulmonary disease (COPD) need to improve blood tests and lung CT to evaluate the causative organisms and treat them according to the causative organisms. Bacterial infection needs to be treated with antibiotics, expectorant drugs are needed if there is sputum that cannot be coughed up, and asthma drugs are needed if there is a significant decrease in lung function.