Vesicular soft tissue sarcoma can typically live up to 20 years. Adenofollicular soft tissue sarcoma is mostly found in adolescent girls, and effective treatment options exist in the clinic at present. However, the specific survival period should be analyzed according to the patient’s personal physical quality, past medical history, pathological biopsy typing and other comprehensive conditions, and actively cooperate with the doctor’s guidance for treatment, so as to prolong the patient’s survival period. Vesicular soft tissue sarcoma is easy to metastasize, the disease progresses extremely slowly, most of the sarcoma cells have a longer survival period after metastasis, as well as a better quality of life, in general, patients in regular hospitals after comprehensive analysis by professional doctors to formulate a systematic treatment plan, the survival period can be more than 20 years, and the longest patients have survived for 30 years.