Stomach bloating and lack of appetite may be caused by functional dyspepsia, chronic gastritis, peptic ulcer and other diseases, which need to be intervened by medication and surgical treatment for the cause of the disease. 1. Functional dyspepsia: Typical symptoms include epigastric discomfort, loss of appetite and belching. Patients need to follow the doctor’s instructions to use domperidone, mosapride and other drugs to promote gastrointestinal dynamics, as well as compound digestive enzymes and other digestive enzyme preparations. 2. Chronic gastritis: common symptoms include postprandial fullness and bloating, loss of appetite, etc. Patients need to follow the doctor’s instructions to use Hâ‚‚ receptor antagonists such as Famotidine and Ranitidine, as well as gastric mucosal protective agents such as aluminum sulfate and colloidal bismuth pectin. If accompanied by psychosomatic factors, also need to follow the doctor’s instructions to use anti-anxiety drugs, such as fluoxetine, paroxetine and so on. In the presence of high-grade intraepithelial neoplasia, it is necessary to consider performing mucosal resection or submucosal dissection. 3. Peptic ulcer: the main symptoms include poor appetite, anorexia and bloating. Patients need to cooperate with the doctor for the treatment of eradication of Helicobacter pylori, and can use proton pump inhibitors such as lansoprazole and pantoprazole, bismuth agents such as bismuth potassium citrate and bismuth bismuth granules, and antibiotics such as amoxicillin and clarithromycin, as prescribed by the doctor. It is recommended that patients with stomach bloating and lack of appetite go to the hospital in time to improve the relevant examinations and cooperate with doctors for active treatment.