There is no such thing as the fastest treatment for cold legs, it is best to follow the doctor’s instructions and choose the appropriate method, you can find out the cause of the physical therapy, medication, surgical treatment, etc., and the persistent discomfort of the legs, you need to consult a doctor for treatment in a timely manner. The common causes of cold legs are rheumatoid arthritis, arteriosclerotic occlusive disease, osteoarthritis, trauma and other diseases, it is recommended to identify the cause of the disease before treatment, targeted treatment. 1. Rheumatoid arthritis: patients can show pain and swelling of the legs, you can take ibuprofen, aspirin and other drugs under the guidance of the doctor, anti-inflammatory pain, relieve swelling, antibiotic treatment if necessary, please follow the doctor’s instructions for medication. 2. Atherosclerotic occlusive disease: anti-platelet drug clopidogrel can be used to prevent thrombosis, the use of nimodipine and other vasodilators to dilate blood vessels, improve microcirculation, if necessary, surgical treatment. 3. Osteoarthritis: Celecoxib can be used to relieve the pain, aminoglycosan chondroitin can also be used to slow down the degeneration of cartilage, the use of red light therapy to alleviate local pain, if necessary, joint replacement. 4. Trauma: patients with muscle, ligament, bone old injury will also have the manifestation of old cold leg, you can go to the hospital in time for x-ray examination, by the doctor targeted treatment. The causes of cold legs are more, may also be related to knee bursitis, gouty arthritis, osteoporosis and other diseases, it is recommended that timely to the hospital to identify the cause of the disease, by the doctor targeted treatment, medication, please follow the doctor’s instructions.