Early symptoms of syphilis in men can lead to genital noma nodules, swollen lymph nodes, and syphilis rash. 1. Chancre nodules: usually 2 weeks after infection, chancre nodules appear in the genital area, such as the coronal groove, penis, glans, or around the anus. The noma may be single or multiple, round or oval, and is painless and itchy. It breaks down easily when touched, is cartilaginous and hard, and forms an ulcer with oozing fluid, which partly subsides on its own, which does not mean that the syphilis is cured. The hard chancre is a characteristic manifestation of early syphilis and an important basis for diagnosing syphilis at an early stage. 2. Enlarged lymph nodes: some patients with early syphilis may have enlarged lymph nodes, mainly in the groin, which are often unilateral, painless, hard and without inflammation on the surface. 3. Syphilis rash: early syphilis patients can also be accompanied by a generalized scattered rash, also known as syphilis rash, rash with polymorphism, a variety of types at the same time, no characteristic. 4. flat warts: in the patient’s anus, genitals, between the toes and other parts of the flat papules, higher than the skin, the boundaries are clear, there may be vesicles, the surface may be covered with gray-white film. The diagnosis of syphilis is mainly dependent on laboratory tests, blood tests for syphilis-related antibodies, and need to be diagnosed in a regular professional hospital under the physician, not self diagnosis based on symptoms.