We have all probably heard of asthma and know that asthma patients are often allergic to pollen, but we have seldom heard of drugs that can also cause asthma. to several hours after the administration of NSAIDs. The attacks are very severe and have a high morbidity and mortality rate [1]. The following is a description of the experience of a patient who had an aspirin-induced asthma attack with shock after taking compounded acetylsalicylic acid. The patient, a middle-aged male, developed shortness of breath and chest tightness after catching a cold more than 10 years ago, and his shortness of breath was mainly expiratory dyspnea, accompanied by cough in paroxysmal non-irritant form, and white mucous sputum in small amount, with occasional yellow sputum. Five days ago, he developed fever after catching a cold, with a temperature of 38.0℃ at the highest, with increased asthma and chest tightness, and coughing and small amount of yellow mucous sputum, and was treated with oral compound acetylsalicylic acid, naproxen and azithromycin. The patient was treated with oral compound acetylsalicylic acid, naproxen, azithromycin and other drugs, but did not improve, and the chest tightness and shortness of breath gradually increased, the family called 120 emergency admission, loss of consciousness at the time of admission, emergency transoral tracheal intubation and ventilator-assisted breathing, the patient’s consciousness was clear, mental incompetence, congestion in the pharynx, multiple ulcers in the mouth, rales could be heard in both lungs, multiple red rashes on the hands and soles of the feet, with itching, urinary catheter placement. Chest CT: bronchitis and pneumonia. Diagnosis: bronchial asthma attack, type I respiratory failure. According to the patient’s recollection, he complained that he had also taken acetylsalicylic acid enteric soluble tablets in the past and worsened suffocated asthma. The final diagnosis was compounded acetylsalicylic acid-induced aspirin asthma. Doxorubicin, salbutamol, budesonide, ipratropium bromide nebulizer inhalation and montelukast tablets were given afterwards, and the wheezing symptoms were significantly reduced. Second, the characteristics of aspirin asthma? Aspirin asthma is a special type of asthma in which patients often have bronchial asthma, nasal polyps, and aspirin allergy, collectively known as the aspirin asthma triad. The incidence of the disease is low, at 1.9%-2.7% of asthma patients, but the morbidity and mortality rate is high. With the widespread use of NSAIDs, its incidence is on the rise [2]. 2. What are the manifestations of aspirin asthma? A few minutes to hours after taking NSAIDs can cause a violent asthma attack, with an incubation period of about 30 min in most patients, or as late as 180 min after taking the drug [3]. Asthma attacks are usually severe, often with cyanosis, conjunctival congestion, profuse sweating, terminal breathing, and irritability. Some patients develop nasal khat symptoms such as runny nose, sneezing, nasal itching, and nasal congestion followed by asthma after taking the drug. 3. What drugs can induce aspirin asthma? The main ones are aspirin (acetylsalicylic acid) and ibuprofen, followed by acetaminophen, naproxen, and diclofenac [3]. 4. the pathogenesis of aspirin asthma? is mostly thought to be related to the inhibitory effect of aspirin and other drugs on respiratory cyclooxygenase. 5. How to use medication when aspirin asthma occurs? Montelukast is a new generation leukotriene receptor antagonist with good efficacy in the clinical treatment of bronchial asthma. Routine use of leukotriene receptor antagonists can effectively prevent NSAID-induced airway constriction with better thoroughness and persistence than allergen- or exercise-induced airway constriction [4]. III. How to recognize and prevent When a physician prescribes drugs in the class of NSAIDs, it is important to inform the physician if he or she has asthma. When using such drugs as NSAIDs, you should pay close attention to your breathing changes for at least 60 min.