In the late stage of cold, the nasal discharge becomes yellow and sticky, which is caused by the combination of viral cold and bacterial cold from the western medicine point of view. At this time, you can add anti-bacterial drugs on top of anti-viral drugs, such as ganciclovir, ribavirin and cytarabine, etc. At the same time, you can add levofloxacin, penicillin, roxithromycin and azithromycin, etc., which can play a role in fighting the yellowing and thickening of nasal mucus at the end of the cold. From the perspective of Chinese medicine, the yellowing of nasal mucus in the late stage of cold is usually due to the combined wind-heat type of cold, which can be treated with drugs such as Chai Hu granules, Da Ye Qing, Pu Di Lan, Jin Yin Hua and so on.