Ms. Lei in Changsha suffers from diabetes, hypertension, Parkinson’s syndrome, hyperlipidemia for more than ten years, and is also a regular patient of the metabolic endocrinology department of a hospital. In the recent week, she always had to feel general weakness, myalgia, restricted activity and poor mental health, her blood pressure and blood sugar were well controlled by self-test, and she also insisted on taking her medication on time, what was going on? I asked her carefully about her condition, and based on the symptoms she described, I first suspected that it was a stroke, so I asked her to be admitted to the hospital for an immediate checkup, and I urgently checked the cardiac enzymes: creatine kinase 30546u/L, creatine kinase isoenzyme 3275u/L, and myoglobin >2000ng/ml. The results came out shockingly, how could the cardiac enzymes be so high? Is it polymyositis or something else? The reason for this is that it is easy to figure out the cause of her weakness, pain, and limited activity caused by the rhabdomyolysis syndrome caused by lipid-lowering drugs. “Rhabdomyolysis syndrome?” Ms. Lei was immediately shocked, “Is it very serious?” I patiently explained to Ms. Lei: rhabdomyolysis syndrome, literally, muscle lysis, looks scary, and it is indeed a life-threatening condition. The disease is caused by various reasons that make the body’s muscle cells dissolve and break the ring, and what’s inside the cells runs outside, causing damage to the body. I told Ms. Lei not to worry, as it was discovered in time and treated in the hospital for a period of time the disease would be controlled and the creatine kinase would return to normal. The cause of rhabdomyolysis syndrome is very complex, and current research points out that there are more than 190 causes, the most common causes are: excessive exercise, muscle crush injuries, metabolic disorders, drugs, etc. Patients generally experience muscle involvement such as pain, pressure, weakness and swelling of the muscles. This disease can easily lead to acute renal failure, mostly acute tubular necrosis. The use of statin lipid-lowering drugs is a relatively common cause of rhabdomyolysis. At present, there are so many patients with diabetes, hypertension, coronary heart disease, atherosclerotic disease, hyperlipidemia, and countless statins. For this reason, I remind all patients to take statins under the guidance of their physicians and to promptly discover the adverse reactions brought about, such as the appearance of symptoms such as no muscle pain, weakness, poor appetite and spirit, to promptly consult a physician to achieve early detection and early treatment of any disease. At the same time, during the taking period regularly see a physician to review blood lipids, cardiac enzymes, liver function and so on. Ms. Lei’s creatine kinase exceeded the normal value by more than 1500 times, which is a serious rhabdomyolysis syndrome, and was fortunately saved from death by timely medical attention.