Pentavalent vaccine and 13-valent pneumonia are generally not recommended to be given at the same time, which may aggravate your child’s adverse reactions. Pentavalent vaccine is a combination of five vaccines, which can prevent diphtheria, tetanus, polio, whooping cough and Haemophilus influenzae type B. The 13-valent pneumonia vaccine is aimed at preventing Streptococcus pneumoniae infections. The 13-valent pneumonia vaccine is designed to prevent Streptococcus pneumoniae infections, and the vaccine produces antibodies in the body to provide active immunity. Pentavalent vaccine is usually associated with side effects such as mild fever, rash or diarrhea. These side effects may be more pronounced if the vaccine is given together with the 13-valent pneumonia vaccine. Therefore, it is recommended to stagger the timing, and its interval should be 2~4 weeks. Children with acute or severe febrile illnesses, or who are using immunosuppressive drugs such as hormones, should delay vaccination. You need to stay for observation for 30 minutes after the vaccination is completed to confirm that there are no adverse reactions before leaving. If adverse reactions occur after vaccination, it is recommended to go to a regular hospital in time to avoid delays.