Sore legs after chemotherapy for cervical lymphoma may be caused by chemotherapy, or it may be caused by tumor metastasis, or it may be caused by the patient’s complication of lumbar disc herniation and other diseases such as cervical spondylosis. 1. Chemotherapy: when patients with cervical lymphoma develop symptoms of leg soreness after chemotherapy, it is considered to be caused by chemotherapy. It may be that the chemotherapeutic drugs used by the patient have caused adverse effects on the nerves or muscles of the patient’s legs, so the patient will have the symptom of leg soreness. 2. Tumor metastasis: if patients with cervical lymphoma have leg metastasis, it will also lead to leg pain after chemotherapy. 3. Lumbar intervertebral disc herniation: lumbar intervertebral disc herniation is mainly caused by degeneration of intervertebral discs, and the main symptoms of patients are lumbar pain, leg pain and other symptoms. If the patients with cervical lymphoma are complicated with lumbar disc herniation, it will also lead to the symptoms of leg pain after chemotherapy. 4. Others: if patients with cervical lymphoma have other diseases such as cervical spondylosis and arthritis, it will also lead to the manifestation of leg pain after chemotherapy. If patients with cervical lymphoma have symptoms of leg pain after chemotherapy, they should consult doctor in time and follow the doctor’s instruction.