Liver transplantation is mainly suitable for patients with small liver cancers with decompensated liver function who are not suitable for surgical resection and ablation treatment, but it should be judged by doctors according to the situation. The indications for liver transplantation for liver cancer mainly include Milan criteria, Pittsburgh criteria and University of California, San Francisco (UCSF) modified criteria, which are different from each other. 1. Milan criteria: the diameter of a single cancerous lesion is ≤5 cm; or the number of multiple cancerous lesions is lang=EN-US>≤3 and the maximum diameter is ≤3 cm; in addition, there is no intrahepatic invasion of large blood vessels and distant metastasis; 3. UCSF modified criteria: ① single tumor diameter less than or equal to 6.5 cm; ② number of tumors less than or equal to 3, each tumor diameter less than or equal to 5 cm, and the total diameter is less than 8 cm; ③ there is no intra-hepatic macrovascular infiltration and no extra-hepatic distant metastasis; 3. Pittsburgh criteria expand the indications for liver transplantation for hepatocellular carcinoma: liver transplantation can be done without intrahepatic macrovascular infiltration, lymph node involvement, and extrahepatic distant metastasis. 4. Hangzhou Criteria: recipients meeting Hangzhou Criteria A are those with tumor diameter ≤8 cm, or tumor diameter >8 cm but AFP ≤100 μg/L; recipients meeting Hangzhou Criteria B are those with tumor diameter >8 cm but AFP 0-400 ng/mL, among which recipients meeting Hangzhou Criteria A have a better prognosis. In conclusion, there are various criteria for liver transplantation. It is recommended to go to a regular hospital for a comprehensive evaluation of the condition and to follow the doctor’s instructions to avoid delaying the condition.