If the skin keeps oozing out, it is usually necessary to strengthen nutrition, diuresis, and in severe cases, it is even necessary to remove the drainage tube and give local suture to get cured. In the clinic, the so-called skin oozing is mainly seen in the abdominal surgery after placing the drainage tube, because of the severe hypoproteinemia and the ascites, after 3-4 days, if it is simple ascites, not necessarily through the drainage tube to drain out, usually through the drainage tube around the oozing, then usually easy to make the wound soaked by the oozing ascites, and need to change the dressing 3-4 times a day or even more times. Because the underlying cause is hypoproteinemia, management requires nutritional enhancement, either enteral or parenteral nutrition, and diuretic infusion of human albumin to increase albumin levels and thereby reduce ascites production. If there is still ascites oozing around the drainage tube after the ascites production is reduced, we can consider removing the drainage tube and suturing the wound locally, meanwhile, strengthening nutrition, diuretic with albumin infusion and other symptomatic treatments, and most of the patients can be cured after the hypo-proteinemia is corrected.