Positive margins after prostate cancer surgery combined with endocrine therapy should be at least 18 months, and how long endocrine therapy should be based on the tumor stage and the patient’s physical conditions.
Prostate cancer is a kind of hormone-dependent cancer, so surgery combined with endocrine therapy can play a better role in inhibiting the growth and development of the tumor.
Since positive margins are a poor prognostic factor, these patients are high-risk prostate cancer patients and should be maintained on long-term adjuvant endocrine therapy for at least 18 months, with regular review of serum PSA level, DRE test, creatinine, hemoglobin, and liver function tests to determine the duration of endocrine therapy.
Endocrine treatment for positive margins after prostate cancer surgery should be carried out in regular hospitals and in accordance with the doctor’s instructions, and should not be self-medicated to avoid delaying the condition.