Puffy face needs to be alert to kidney disease or thyroid disease, etc., as follows: 1. Chronic renal insufficiency, nephrotic syndrome, glomerulonephritis, etc.: Patients often have eyelid and facial edema, mainly due to hypoproteinemia caused by increased urine protein, which can appear as eyelid edema. Usually patients need to do further routine urine examination, qualitative urine protein examination and renal function examination to clarify the diagnosis and carry out symptomatic treatment. 2. Mucinous edema caused by hypothyroidism: Patients may develop ocular and facial edema, and usually need to do further thyroid function examination, including T3, T4, free T3, free T4 and TSH examination, and need to supplement thyroxine to improve symptoms after the diagnosis is clear.