Causes of puffy eyes: First, it is possible that the pillow is too low during sleep, especially in patients with heart disease, if the pillow is too low there will be sagging edema. Sodium and water retention caused by drinking too much water or eating too much salt before sleep. Third, caused by renal disease, such as acute and chronic glomerulonephritis, nephrotic syndrome, acute and chronic renal failure caused by water retention. Hyperthyroidism protruding eyes, in hyperthyroidism there will be swelling of the eyes. Allergy or mosquito bites. Diseases of the eyes themselves. Hypoproteinemia caused by various liver diseases or malnutrition.