Chronic granulomatous inflammation may be caused by inflammation due to foreign body, tuberculosis, leprosy, etc. Depending on the situation, medication and surgery can be used to improve the condition. 1. Inflammation caused by foreign body: If there is a trauma, failure to remove the foreign body in time will lead to the formation of chronic granulomatous inflammation. The wound should be cleaned of foreign bodies and sterilized. If the granuloma is large, it needs to be surgically removed. 2. Tuberculosis: If chronic granulomatous inflammation exists in the lungs, it is necessary to be alert to the occurrence of tuberculosis. Once the diagnosis is confirmed, isoniazid, rifampicin, pyrazinamide, ethambutol and other anti-tuberculosis drugs should be used under the guidance of the doctor to carry out early, adequate and standardized drug treatment. 3. Leprosy: Chronic granulomatous inflammation may also be caused by leprosy, which can be treated with drugs such as rifampicin, ampicillin and aminophenazine under the guidance of doctors. Chronic granulomatous inflammation may also be caused by other diseases, such as tuberculosis, etc. It is recommended that the patient actively consult the doctor and cooperate with the doctor to carry out the treatment, and avoid self-medication, so as to avoid delaying the condition. The above drugs should be used under the guidance of a physician.