Wisdom teeth can be excruciatingly painful as they have to push through the muscle tissue during the growth process. Clinical removal of wisdom teeth includes both traditional extractions as well as minimally invasive extractions. The former may have pain that lasts for about a week, while the latter may have no significant pain for about 24 hours. In exceptional cases, the pain may continue for a long time. The traditional method of wisdom tooth extraction is mainly applied by hammering and chiseling, but this method has a major disadvantage in that it tends to cause damage to other teeth and the duration of pain that occurs when wisdom teeth are extracted is related to the difficulty of the tooth extraction. After wisdom tooth extraction, it is recommended to take some anti-inflammatory and pain-relieving medications, and the pain will generally be removed within a week. Minimally invasive tooth extraction is a method that is very widely used in clinical practice to extract wisdom teeth. This method requires high technical level of doctors and hospital equipment, and there is no risk of causing complications. Moreover, this procedure is less traumatic to the teeth in the body’s mouth and will not cause bleeding, pain and swelling of the gums, and the pain will generally be removed within 24 hours. Exceptionally, due to the location and depth of the wisdom tooth and infectious reasons, empty socket syndrome can occur after wisdom tooth removal. This can cause the extraction of wisdom teeth and persistent painful discomfort, usually for about 1 month. This period requires constant trabecular filling in order for the trabeculae to return to normal and for the toothache to disappear. Also, after having a tooth extraction, do not smoke, drink alcohol, or eat foods that are more stimulating and too hard in the near future. Do not rinse your mouth or brush your teeth for 24 hours. Usually the duration of pain after wisdom tooth extraction is related to the method chosen to remove the wisdom tooth and the degree of difficulty.