Epigastric pain in the middle of the right side may be caused by colon disease, cholecystitis, costochondritis, shingles and other pain. 1. Colon disease: such as colon spasm, inflammation of the colon, etc., may cause epigastric pain in the middle of the right. Patients with colitis can take oral antibiotics and anti-inflammatory drugs under the guidance of a doctor, such as metronidazole, sulfasalazine, dexamethasone, etc. For patients with adverse drug reactions, it is recommended to seek medical attention as soon as possible. 2. Cholecystitis: Cholecystitis may occur at the same time with gallbladder stones, mainly in the middle of the epigastrium after eating a full meal to the right pain. Under the guidance of the doctor, patients can take analgesic and antispasmodic drugs to control the condition, such as pethidine, clindamycin and so on. 3. costochondritis and herpes zoster: the patient manifests neuropathic pain, accompanied by pain in the right upper abdomen, there will be a rash, localized pressure and pain and other symptoms. It is recommended that patients with pain symptoms, should rest, do not overwork, but also pay attention to try not to do physical labor. Serious symptoms should seek medical attention in time to avoid aggravation of the condition, resulting in serious adverse consequences.