Some patients with bone metastases from liver cancer are usually enough to survive for 2-3 years after comprehensive treatment. If lumbar, thoracic and cervical metastases lead to paralysis, the survival period may be shorter due to the inconvenience of further medical consultation, as well as the inconvenience of nursing. Hepatocellular carcinoma belongs to a relatively high malignant tumor and is prone to distant metastasis, which requires comprehensive treatment to prolong the survival period, including primary foci treatment and metastatic foci treatment. 1. Primary foci treatment: metastatic foci can be treated by intervention, radiofrequency ablation and perfusion to control primary foci and prevent further metastasis of cancer cells; 2. Treatment of metastatic foci: use drugs that inhibit bone destruction to reduce bone destruction. Radiotherapy or painkillers can also be used to treat pain caused by bone metastasis. If paralysis is caused by bone destruction in thoracic, cervical and lumbar vertebrae, an orthopaedic surgeon needs to be invited to consult with the patient in time for judgment. If the patient is at risk of paralysis, further surgical treatment is needed to reduce the risk of paralysis. It is recommended that patients seek timely consultation and active treatment under the guidance of a physician to prolong survival.