In women of childbearing age, if they do not have menstruation for four months, the first case may be pregnancy, the second case may also be affected by mental and work pressure, hormonal disorders and menstrual disorders, the third case, when women suffer from polycystic ovary syndrome, pituitary tumors, can also lead to menstruation, the fourth case, when women suffer from hyperthyroidism or hypothyroidism and other endocrine disorders, can also lead to amenorrhea. The fourth situation, when women suffer from endocrine disorders such as hyperthyroidism or hypothyroidism, can also lead to amenorrhea. If a woman does not have a period for four months, she should first have a gynecological ultrasound to rule out pregnancy, then she should check the sex hormone six items, and if it is caused by hormonal disorders, she should be given estrogen and progesterone for standardized treatment. If the condition is caused by polycystic ovary syndrome or pituitary tumor, comprehensive treatment should be given. If the absence of menstruation is caused by hyperthyroidism or hypothyroidism, active treatment of the primary disease is required.