The mute state often appears during the phase of severe depressive episodes, when it is quite difficult to distinguish from the catatonic type of schizophrenia, but depressive mute often occurs gradually, often preceded by depressed mood, and mute is often incomplete, with rare symptoms such as inability to take care of oneself, increased muscle tone, waxing flexion, and air pillow, and is not accompanied by catatonic excitement. On closer inspection, one can also notice that the patient’s eyes tend to maintain some communication with the examiner, either with tears in the orbits or in response to emotional stimuli, and that once the lignocaine is lifted, the depressive features of depression are revealed, in contrast to the indifference and psychotic symptoms predominant in schizophrenia. The disease begins in middle age, progresses slowly, worsens progressively, and may develop on the basis of severe depression, with the rigidity gradually resolving as the depression improves. Depressive wood stiffness is commonly associated with schizophrenia, so the following preventions should be made. 1. Carry out genetic counseling. For patients with schizophrenia who are already in the age of marriage and childbirth, it should be recommended to avoid marriage and childbirth until symptoms have disappeared, especially if both parties have suffered from schizophrenia. 2. Carry out community mental health promotion for early detection and treatment. The occurrence and relapse of schizophrenia is mostly related to adverse mental stimuli in the surrounding environment, so it is very important to create a friendly and humane environment. For people who have had psychotic symptoms, particular attention should be paid to care and love, and avoid giving adverse mental stimuli.