Patients in the use of clotrimazole vaginal tablets for the first two days, not be able to coitus, mainly because of the following two factors: first, patients use clotrimazole vaginal tablets, generally mainly for the treatment of mycobacterial vaginal inflammation. Inflammation will lead to localized congestion and edema of the vaginal wall of the patient, so the patient will feel dryness, pain and discomfort during coitus, which may cause damage to the vaginal wall in severe cases, so there is damage to the patient. In addition, mycobacterial vaginal inflammation can be cross-infected, if the patient in the inflammation of the treatment period of coitus, it is likely that the inflammation will be transmitted to their sexual partners. The patient’s sexual partner itself with bacteria, coitus will lead to female cross-infection, so the patient in the inflammation of the treatment period absolutely can not coitus. Secondly, clotrimazole vaginal tablets put a piece can continue to be effective for three days, if the drug on the first two days of coitus, will greatly reduce the effect of the drug.