Waking up with blood in the mouth is most often seen in gingivitis or apical abscess. Oral hygiene is not good teeth around a large number of soft dirt or tartar, long-term pressure on the gums so that the gums bleed, gingivitis acute stage in the mouth after sleeping there will be blood. Need timely treatment, such as scaling and medication. Periapical abscess, is not timely treatment of dental caries lead to pus in the nerve, inflammation break through the mucosa of the gums red and swollen or pus, can also lead to blood in the mouth after waking up. In this case, root canal treatment is needed, and the symptoms can be relieved after the inflammation is controlled. Therefore, waking up with blood in the mouth is considered to be gingivitis or apical inflammation, and need to go to the hospital stomatology department for scaling or dental treatment. It is recommended to consult a doctor in time to clarify the cause of the disease and treat the symptoms.