The medication for swollen penile skin varies according to allergy, inflammation and trauma, including loratadine tablets, cefixime tablets, furosemide and so on. 1. Allergy: If the patient is allergic to the penis skin swelling, then you can use loratadine tablets, mometasone furoate gel and other drugs under medical advice to improve the swelling through anti-allergy treatment. 2. Inflammation: due to Pseudomonas aeruginosa, staphylococcus bacteria and other causes of inflammation of the foreskin and glans, caused by the patient’s penile skin swelling, the patient can be prescribed the use of cefixime tablets, cloxacin capsules and other drugs for treatment, through the anti-infective treatment to alleviate the swelling. 3. Trauma: trauma or foreskin incarceration caused by swelling of the penile skin, you can use furosemide, hepatic saponin sodium and other drugs under medical supervision, can play a role in improving the effect of edema. For penile skin swelling, patients can also through local hot compresses, physiotherapy and other methods to alleviate the symptoms, and pay attention to reduce the adverse stimulation of the penile skin. At the same time, patients need to pay attention to the doctor’s guidance under the use of drugs, not blindly self-medication.