There is no clinical statement about which is better, lidocaine or bupivacaine. Both are a kind of local anesthesia drug, only the scope of application is different. Lidocaine belongs to the amide class of local anesthetic drugs, for the medium-acting local anesthetic, and is less toxic than bupivacaine. It has a fast onset of action, wide dispersion, no obvious vasodilatation effect, and is mostly used in small surgical procedures and the treatment of cardiac arrhythmia. Bupivacaine belongs to the ester class of local anesthetics, which is a long-acting local anesthetic. Clinically, it is mainly used for mucosal anesthesia, such as mucosal surface anesthesia for oral cavity, ear, nose, throat and eye surgery. Because of its high toxicity, it is generally not applied to local infiltration anesthesia. Therefore, clinically there is no lidocaine and bupivacaine which is better, the specific disease needs to be under the guidance of a professional doctor, the use of appropriate drugs for treatment.