Serpentine is clinically known as herpes zoster, and herpes zoster can have systemic symptoms such as fever, fatigue, not wanting to eat, and lack of energy before there is the appearance of blisters. And in the part where there is the appearance of blisters, there will be obvious discomfort on the skin, some patients for example have itching sensation. Some patients have obvious burning or even burning pain, and some patients will have more obvious pain and allergy after touching it. Generally before the appearance of blisters is localized erythema, then the appearance of soybean-sized papules, and then from the papules to the typical blister-like manifestations. Herpes zoster is usually more common in patients with poorer immunity and resistance.