Corner of the mouth lines can be removed by surgical wrinkle removal, injection wrinkle removal, laser wrinkle removal. 1. Surgery to remove wrinkles: the common “face lift”, the skin of the face and neck and its deep surface of the tissue, structure separation, to the back of the upper lift and fixed, remove excess skin and then re-suture. The skin is then lifted upwards and fixed, and the excess skin is removed and sutured back together. The aim is to tighten the facial skin and improve the appearance of wrinkles. 2. Wrinkle injection: common hyaluronic acid, autologous fat, collagen and other filler injections and botulinum toxin injections, filler injections can be used to improve the static wrinkles at the corners of the mouth by replenishing the capacity of the subcutaneous soft tissues, and botulinum toxin injections can be used to improve the dynamic wrinkles at the corners of the mouth by inhibiting the contraction of the local muscles. 3. Laser wrinkle removal: carbon dioxide laser, radio frequency, ultrasonic knife and other photoelectric treatment can stimulate the subcutaneous production of new collagen tissue, to achieve the reconstruction of the dermal framework structure, to achieve the purpose of removing wrinkles. Patients who wish to improve the corners of their mouths are advised to go to a regular medical institution and choose the appropriate treatment.