Small bumps on the vaginal opening may be related to bacterial infection caused by inadequate vulvar cleansing. Since the vaginal opening is often wrapped by the labia, if the vulva is not cleaned in time, it is easy to cause bacterial infection, or even retrograde infection causing vaginal inflammation. If the patient has obvious pain, vulvar itching, vaginal discharge odor and other symptoms, then consider the following conditions: 1, folliculitis: mainly due to improper cleaning of the vulva caused by bacterial infections, manifested as a single or multiple pimples, and gradually formed pustules and accompanied by tenderness, and the continued development of the boils can be formed. Generally, mild folliculitis can disappear on its own after keeping the vulva clean. If it persists or even becomes more serious, it can be treated with mupirocin ointment, fusidic acid cream and other medicines under the guidance of the doctor; 2. Vulvar eczema: due to long term living or working in hot and humid environment, as well as stimulation of vulvar secretion and sweat, it may cause vulvar eczema, which manifests itself as the redness and swelling of the vaginal opening and perineum, which is similar to a pimple. Blisters, shaped like small bumps, often accompanied by burning pain, may break and ooze. It is recommended that patients change light and breathable underwear, timely cleaning of vulvar secretions, serious cases can be prescribed the use of hydrocortisone cream and other medications; 3, mycosis fungoides: patients can be found in the inner labia minora white lumps, wipe off the surface of the trauma can be presented red, swollen, like a small pimple, and at the same time, patients can be accompanied by burning sensation in the vagina, itching, pain and other symptoms. It is recommended to visit the hospital for antibacterial treatment. Follow the doctor’s instructions to use drugs, such as miconazole suppositories placed deep in the vagina, oral fluconazole, and glucocorticoids, etc.; 4, Bartholin’s gland cysts: also known as vestibular gland cysts. Vestibular gland is located behind the labia majora, due to obstruction of the gland ducts, secretion stagnation and other factors caused by cysts, small cysts are mostly asymptomatic, similar to a small pimple, but large cysts can often be manifested as pain, foreign body sensation or even pus, it is recommended that the patient go to the hospital in a timely manner to clarify the degree of development of the cysts can be taken to the cyst stoma, incision and drainage, adenomectomy, etc. for treatment; 5, viral herpes: viral herpes is caused by the Herpes virus infection caused by the disease, type II mainly caused by genital infection, manifested in the labia major and minor, clitoris, vaginal opening and other parts of the small blisters, shaped like small bumps, accompanied by itching, burning pain and other symptoms, it is recommended that the patient in the doctor’s guidance to actively carry out antiviral treatment; 6, warts: warts is a sexually transmitted disease caused by the human papillomavirus (HPV) infection, often manifested in the lips of the vagina, vaginal opening, The most important thing to remember is that it is not a good idea to have a single, soft, small particle, like a small pimple, in several parts of the body, such as the clitoris. With the development of the disease can gradually form multiple or groups of papillary, cauliflower, corns and other forms of warts, can be accompanied by local itching, pain, bad smell, bloody urine. Patients should go to the hospital immediately for treatment, including cryotherapy, laser treatment, electrocautery treatment and other physical therapies, as well as medication with imiquimod cream, tincture of onychomycetin, trichloroacetic acid and other medications. Early treatment can prevent the development of lesions, reduce the difficulty of treatment, generally a better prognosis, but the recurrence rate is higher; 7, pseudo warts: preferred in the vaginal opening, urethral opening, labia minora, manifested as a uniform distribution of small pimples, may be in the initial single, but with the development of the disease can appear pompholytic or caviar-like pimples, belong to the benign disease, there is a certain degree of self-limitation, may not be a special treatment. If there is obvious itchiness or other uncomfortable symptoms, the lesion tissue can be removed by laser or freezing.