Antagonist program is a kind of down-regulation program in IVF transplantation, in the process of IVF transplantation through the antagonist program, it is necessary to closely monitor the changes of sex hormones in the body as well as the growth and development of follicles, and timely addition of antagonists to counteract the premature emergence of the peak value of LH in the body, to prevent premature maturation of follicles and ovulation, so that the follicle maturation time can be synchronized with the development of endometrium, which is beneficial to strive for the most appropriate time to remove mature eggs for fertilization. This is conducive to striving for the most suitable time to take out mature eggs for fertilization, which will improve the success rate of IVF to a certain extent. However, which program to adopt when doing IVF depends on the specific situation of the patient, and the antagonist program is not suitable for all IVF patients. After using the antagonist program, you need to increase the dose of progesterone to avoid insufficient levels of progesterone, which may affect the success rate of IVF.