There is no correlation between thumbnail vertical lines and liver cancer. Common causes of thumbnail vertical lines include normal physiological phenomena, nail diseases and peripheral diseases. The first is that as age increases, vertical lines in the nail may occur due to localized stress without accompanying other lesions in the nail. Lesions. In addition, psoriasis and repeated inflammation around the nails may cause vertical lines on the thumbnail, and then dermatologic consultation is required. The main symptoms of hepatocellular carcinoma do not include thumbnail wrinkles, but mainly include abdominal pain, abdominal distension, jaundice, skin bruises, etc. If the above symptoms exist, it is necessary to consult a doctor in time, improve tumor markers, abdominal ultrasound, abdominal CT and biopsy to make it clear. There is no correlation between thumbnail wrinkles and liver cancer, so there is no need to be overly nervous about thumbnail wrinkles, check whether there are any diseases around the nails, and seek timely medical treatment if necessary.