One eyeball is high and one eyeball is low, which refers to the asymmetry of the eye positions of both eyes. It may be caused by congenital developmental abnormality, orbital swelling, or trauma to the eyes. 1. Congenital developmental abnormality: If the patient’s extraocular muscles are congenitally underdeveloped, it may cause the patient’s eyes to be unevenly positioned and vertical strabismus, which can usually be corrected through surgery. 2. Orbital mass: when the patient has occupying lesions such as tumors and cysts in the orbital area, it may not only cause the patient’s eye position to be uneven, but also lead to the patient’s eye movement limitation, blurred vision and other uncomfortable symptoms. 3. Eye trauma: If one side of the eye is injured and the eyeball is involved, the patient may have the symptoms of asymmetry and asymmetry. It is recommended that patients with asymmetric eye position should consult a doctor in time to assess their condition and follow the doctor’s instructions for treatment.