Fifty-three years old hair loss is serious, hair will grow back. Hair has its own growth and aging cycle, physiological hair loss need to ensure nutrition, strengthen scalp care. If there is pathologic hair loss, you need to find the cause of the disease, symptomatic treatment. 1. Physiological hair loss: common such as lack of nutrition, endocrine disorders, mental stress. Especially with ageing, hair follicles shrink and hair is more likely to fall out. Patients should actively improve their daily routine, ensure nutrition, strengthen scalp care, can use selenium disulfide shampoo, with oral folic acid tablets, vitamin B6 or cystine tablets, activate the hair layer, which can help hair growth. 2. Pathological hair loss: Lupus erythematosus and alopecia folliculitis can cause pathological hair loss. For hair loss caused by lupus erythematosus, hydroxychloroquine and prednisone can be taken orally to reduce immune inflammation and alleviate hair loss. For alopecia areata folliculitis, red helium-neon laser irradiation can be applied, together with ointment such as halomethasone ointment, to constrict the blood vessels and alleviate the symptoms. The use of the above drugs should strictly follow the doctor’s instructions. It is recommended that patients go to the hospital in a timely manner to improve the examination, clear the cause of the disease under the guidance of the doctor to standardize the treatment, and actively treat the primary disease, hair loss can be gradually relieved.