1. Organic lesions such as prostatitis can cause the prostate to secrete less active substances, resulting in semen not liquefied or poor liquefaction, semen particles, should be timely medical treatment, under the guidance of the doctor to standardize the use of medication, such as the use of of oxyfloxacin, tamsulosin and so on. 2. Organic lesions can also be seen in seminal vesiculitis, mostly caused by retrograde bacterial infection, manifested in yellow granular semen, the treatment is mainly medication, such as ofloxacin, ceftriaxone and so on. 3. Physiological changes such as cold and wet weather, can cause semen not liquefied, there can be particles precipitation, this situation need to pay attention to warm, ensure that the perineum is dry and clean, exercise can be. 4. Long-term no sex can also lead to semen particles, this situation needs to be regular sperm discharge, and add physical exercise. Whether it is organic lesions or physiological changes, you need to take measures, can not be left unattended, if the long term does not relieve, should be timely medical treatment.