The disadvantages of removing half of the thyroid gland are mainly as follows: hypothyroidism, dyspnea, hoarseness, bleeding and fluid accumulation in the wound, etc. Though there may be disadvantages, you should not blindly avoid the surgery when there are indications such as thyroid cancer. 1. Hypothyroidism: The thyroid gland is an endocrine organ that secretes thyroid hormones. After half of the thyroid gland is removed, the thyroid gland will not secrete enough hormones, which will lead to hypothyroidism, which can be treated with alternative treatment by levothyroxine sodium. 2. Difficulty in breathing: after thyroid surgery, the wound may accumulate fluid, bleeding, edema, and may compress the trachea, which will lead to difficulty in breathing. 3. Hoarseness: after the surgery, due to tissue edema and other reasons, there is a possibility of compression of the recurrent laryngeal nerve, or damage to the recurrent laryngeal nerve due to improper surgery, which will lead to hoarseness. It is recommended that thyroidectomy be performed in a regular hospital.