Pain in the center of the foot when pressed is usually seen in the following two types of conditions: first, calluses that occur in the center of the foot, also known as corns. It is a cortical hyperplasia that occurs when the skin on the bottom of the foot rubs repeatedly against the shoe, and is often accompanied by significant pain when pressed. The treatment can be external application of corns cream, or use a knife to remove the hyperplastic, hardened cortex layer. The second type, the heart of the foot pressed pain is also common in the plantar fasciitis, which is a chronic inflammation of the tendon attachment points and bone on the bottom of the foot. It is common in patients who exercise a lot, walk or run for long periods of time and long distances. For treatment, hot water foot soaks, localized fascial cavity shock therapy, microwaves, and baking lamps can help relieve symptoms. If necessary, local closure therapy or surgery to loosen the chronic inflammatory fascia can provide quick relief.