Initially, 25 hydroxyvitamin D deficiency can cause symptoms such as easy startling, excessive sweating, crying, sleep disturbances, O- or X-shaped legs and muscle weakness.
Severe 25 hydroxyvitamin D deficiency can lead to rickets with symptoms such as bone and joint pain, insomnia, nervousness, and diarrhea. In severe cases of rickets, respiratory, circulatory, digestive, and immune system disorders can occur, in addition to having an effect on a child’s intelligence.
Vitamin D can only be converted to 25 hydroxyvitamin D through kidney and liver activation to make it work, so if there are patients with liver or kidney insufficiency or damage, it is necessary to take active vitamin D directly. This is because such patients are not able to metabolize vitamin D into the active product.
For patients with normal renal and hepatic function only need to take vitamin D can promote the absorption of calcium, to maintain normal bone growth and development.