Patients with gastric cancer presenting with blood vomiting should first actively establish intravenous access, intravenous fluid augmentation, and monitor the change of blood pressure. At the same time, cross-matching of blood, intravenous infusion of suspended red blood cells and plasma to increase plasma colloid osmotic pressure and replenish coagulation factors should be performed to avoid the occurrence of asphyxia due to massive vomiting of blood, which can be life-threatening in severe cases. Intravenous anti-infective therapy and hemostatic drugs, such as hemagglutinin or snake venom hemagglutinin, should also be applied. And proton pump inhibitors should also be applied, the most common one is omeprazole, which can be administered intravenously and has a certain effect of inhibiting stomach acid and stopping bleeding. The most effective treatment for vomiting blood caused by gastric cancer is surgery to remove the tumor.