After gastroscopy, it is not normal to wake up in the second half of the night. After gastroscopy, the quality of sleep may be affected on the same night due to the fear of gastroscopy or the effect of anesthesia drugs used during gastroscopy, but this abnormality will only occur for 1~2 days and will not occur all the time, and waking up in the middle of the night after sleeping all the time has nothing to do with gastroscopy, so you can pay attention to your body to see if there is any gastric disease that will affect your sleep after gastroscopy. In addition, waking up in the middle of the night may be related to poor sleep environment, overuse of the brain, physical fatigue, sleeping too much during the day, emotional disorders, heart disease, anemia, or other systemic diseases. Therefore, after gastroscopy, waking up in the middle of the night after sleep is necessary to go to the hospital immediately for further examination of the cause of sleep disruption and targeted treatment.