The follicle grows up and is not discharged, indicating the existence of ovulation disorder, which may be related to polycystic ovary syndrome, premature ovarian failure, endometriosis and other factors, and need to be analyzed specifically. 1. Polycystic ovary syndrome: at this time, the body produces too much androgen, which will inhibit ovulation and may lead to the follicle not being discharged after it grows up. 2. Premature ovarian failure: at this time, the level of estrogen in the body is in a low state, can not produce corresponding stimulation of the follicle, resulting in the follicle can not be discharged. 3. Endometriosis: at this time there is inflammation in the pelvis stimulation, may have an impact on the tissues around the ovary, so that the follicle is difficult to discharge. When a woman has a follicle that cannot be discharged after it grows, she needs to go to the hospital in time, and under the guidance of the doctor, carry out standardized treatment to promote the smooth discharge of the follicle and complete fertilization.