If the first time you take Yosmin, how long you can have intercourse, will not affect the contraceptive effect, because Yosmin is not after taking the drug will play a contraceptive effect, but through the inhibition of ovarian ovulation, and change the thickness of the uterine lining, make the uterine lining thinner, to prevent the fertilization of the egg to bed, and then to achieve the contraceptive effect. Therefore, as long as you follow the instructions of Yosmin and don’t miss any doses, most of them will achieve good contraceptive effect in clinical practice. However, not all patients who take Yosmin will play 100% contraceptive effect, so if you do not have a period after taking Yosmin, we should also rule out the possibility of pregnancy.