Most tympanic membrane perforations are caused by trauma or inflammation, and patients often experience ear pain, bleeding from damage to the external ear canal, as well as tinnitus and hearing loss. Depending on the cause, the patient’s symptoms may vary and so may the treatment. In the case of tympanic membrane perforation caused by trauma, some patients will experience sudden ear pain, hearing loss with tinnitus, and a small amount of blood in the external ear canal; some patients will also experience a feeling of stuffiness in the ear, dizziness, nausea, or even vomiting. Treatment generally involves avoiding water contamination of the external ear canal and preventing acute inflammation of the middle ear cavity. In general, most tympanic membrane perforations can heal in 1-3 months. If the tympanic membrane is perforated due to acute otitis media, most patients will have symptoms such as ear pain, pus flowing from the external ear canal, hearing loss and tinnitus, as well as systemic symptoms such as headache and fever. The first step in treatment is to use hydrogen peroxide to cleanse the outer ear canal and middle ear cavity of purulent secretions and then soak the affected ear with oxyfloxacin ear drops; oral antibiotics, such as amoxicillin clavulanate potassium, should be taken to control inflammation. It is also important to avoid water in the affected ear and to prevent colds. In the case of tympanic membrane perforation caused by chronic otitis media, patients usually have no obvious symptoms of discomfort, and most of the symptoms are hearing loss in the affected ear, which may be accompanied by tinnitus. Most tympanic membrane perforations caused by chronic otitis media require surgical treatment. Therefore, the symptoms of tympanic membrane perforation vary, but most of them are the same: pain, small amount of bleeding, hearing loss and tinnitus, etc. The treatment of tympanic membrane perforation depends on the cause and symptoms of the patient. （The treatment of tympanic membrane perforation is based on the cause and symptoms of the patient. (For specific medication, please combine with the clinical situation and be guided by the doctor’s interview)