Burns leading to death usually occurs in patients with large-area burns, mainly because shock, infection, respiratory distress, and other complications will occur after burns. 1. Shock: after extensive burns, a large amount of extravasation of body fluids exceeds the body’s compensatory range, resulting in a sharp decline in the effective circulating blood volume, which can cause hypovolemic shock death. 2. Infection: after skin burn, the barrier protection function of the skin is impaired, and the wound exudate contains a large amount of protein, which is conducive to the growth of wound bacteria, which can lead to wound infection, sepsis and other organ failure and death. 3. Respiratory difficulties: patients with severe head and neck burns are prone to swelling, which can lead to tracheal edema, respiratory difficulties, asphyxia and other conditions, and in severe cases, death can also occur. 4. Other complications: patients with extensive burns are prone to complications, such as acute renal failure, acute respiratory distress, acute heart failure, death and so on. It is recommended that burns should be treated in a timely manner, and usually pay attention to do a good job of fire prevention to avoid accidental burns.